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On-phage (bivalent)
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Off-phage (monovalent)
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|---|
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Clone
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IC50for 5-HelixA/nM
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IC50for 6-Helix-FdA/nM
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IC50for 5-HelixA/nM
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IC50for 6-Helix-FdA/nM
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|---|
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D5 WT
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0.1 (0.07-0.1)
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11 (8–15)
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7.3 (5.3-10)
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290
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25B8
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3.1 (1.8-5.3)
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~100
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NDB
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NDB
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25C10
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1.8 (1.3-2.7)
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28 (21–37)
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56 (40–79)
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NC
C
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25D8
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5.8 (4.2-7.5)
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~3000
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NDB
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NDB
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25A10
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1.6 (1.3-2.0)
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260 (150–450)
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5.4 (3.8-7.7)
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~500
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25D9
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1.7 (1.4-2.1)
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230 (150–360)
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NDB
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NDB
|
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25G8
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7.2 (4.2-12.3)
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300 (120–750)
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NDB
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NDB
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25C6
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32 (24–44)
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~1000
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NDB
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NDB
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25C12
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100 (31–300)
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~1000
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NDB
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NDB
|
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25D6
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0.5 (0.3-0.8)
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~80
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NDB
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NDB
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25D3
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17 (9.9-30)
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170 (70–390)
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NDB
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NDB
|
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25F1
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0.9 (0.7-1.2)
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40 (20–79)
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NDB
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NDB
|
|
25B6
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0.3 (0.2-0.4)
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23 (15–36)
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0.6 (0.3-1.0)
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94 (56–160)
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25F10
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0.2 (0.2-0.3)
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22 (16–30)
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NDB
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NDB
|
|
25A12
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2.2 (1.2-4.0)
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220 (70–670)
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34 (23–52)
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280 (120–640)
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- A 95% Confidence intervals from data fitting are shown in parentheses.
- B ND, not determined.
- CNC, no convergence observed upon data fitting, suggesting weak or insignificant binding.
